L-Glutamine
The most abundant amino acid in the body, heavily consumed by immune cells and the gut lining. Plasma levels can drop significantly during intense exercise or physiological stress. Short plasma half-life due to rapid tissue uptake.
Projected serum levels — 5 g (≈ 5k mg), once daily
Maintenance schedule: 5 g (≈ 5k mg) once daily (oral).
Modeled steady state after ~1 days: peak ≈ 2.2k mg, trough ≈ 0.000 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Amino Acid
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 1 h
- Common dose
- 5 g (≈ 5k mg)
- Suggested maximum
- 30 g/day
- Reference dose range
- 2.5–30 g (single dose)
- Suggested cadence
- once daily
Documented interactions
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moderate
EAAs (Essential Amino Acids) + L-Glutamine
EAAs (Essential Amino Acids) and L-Glutamine both push the endogenous amino acid pool and mtor in the same direction.
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moderate
L-Leucine + L-Glutamine
L-Glutamine and L-Leucine both push the endogenous amino acid pool and mtor in the same direction.
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moderate
Whey Protein Concentrate + L-Glutamine
L-Glutamine and Whey Protein Concentrate both push the endogenous amino acid pool and mtor in the same direction.
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moderate
Whey Protein Isolate + L-Glutamine
L-Glutamine and Whey Protein Isolate both push the endogenous amino acid pool and mtor in the same direction.
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watch
Egg White Protein + L-Glutamine
Egg White Protein and L-Glutamine both push the endogenous amino acid pool in the same direction.
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watch
Glycine + L-Glutamine
L-Glutamine and Glycine both push the endogenous amino acid pool in the same direction.
Serum checks 12 modeled interaction pairings for l-glutamine across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.
Research behind this entry
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L-glutamine supplementation in recovery after exercise: effect on body composition and performance
Glutamine supplementation (0.3g/kg) reduced muscle soreness and strength loss after eccentric exercise, suggesting a role in exercise recovery, particularly during periods of high training volume.
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A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects.
This citation reports a human clinical study involving L-Glutamine. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
2 published studies referenced in the app, each with a plain-language summary.