Whey Protein Isolate
Fast-absorbing, highly filtered whey protein with 90%+ protein content and minimal lactose/fat. Rapidly elevates plasma amino acids, peaking around 60-90 minutes post-ingestion.
Projected serum levels — 25 g (≈ 25k mg), once daily
Maintenance schedule: 25 g (≈ 25k mg) once daily (oral).
Modeled steady state after ~1 days: peak ≈ 20.6k mg, trough ≈ 869 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Protein
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 4.9 h
- Common dose
- 25 g (≈ 25k mg)
- Suggested maximum
- 75 g/day
- Reference dose range
- 12.5–75 g (single dose)
- Suggested cadence
- once daily
Documented interactions
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caution
Iron (Bisglycinate) + Whey Protein Isolate
Dairy-derived proteins (whey, casein) can reduce non-heme iron absorption by 50-60% when taken together due to calcium and caseinophosphopeptide content.
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moderate
EAAs (Essential Amino Acids) + Whey Protein Isolate
EAAs (Essential Amino Acids) and Whey Protein Isolate both push the endogenous amino acid pool and mtor in the same direction.
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moderate
L-Glutamine + Whey Protein Isolate
L-Glutamine and Whey Protein Isolate both push the endogenous amino acid pool and mtor in the same direction.
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moderate
L-Leucine + Whey Protein Isolate
L-Leucine and Whey Protein Isolate both push the endogenous amino acid pool and mtor in the same direction.
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moderate
Whey Protein Concentrate + Whey Protein Isolate
Whey Protein Concentrate and Whey Protein Isolate both push the endogenous amino acid pool and mtor in the same direction.
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watch
Egg White Protein + Whey Protein Isolate
Egg White Protein and Whey Protein Isolate both push the endogenous amino acid pool in the same direction.
Serum checks 14 modeled interaction pairings for whey protein isolate across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.
Research behind this entry
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Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men
Whey protein ingestion resulted in greater postprandial muscle protein accretion than casein or casein hydrolysate in older men, attributed to its faster digestion and higher leucine content.
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The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength
Whey protein supplementation during resistance training increased lean tissue mass and bench press strength compared to placebo over 6 weeks.
2 published studies referenced in the app, each with a plain-language summary.