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Enalaprilat

ACE Inhibitorprescriptioniv · inferred

Active diacid form of enalapril; formed by hepatic esterase de-esterification. Long-acting ACE inhibition. Also directly available IV.

Projected serum levels — 1.3 mg, custom (shown daily)

Enalaprilat
Enalaprilat modeled serum levels, 1.3 mg custom (shown daily) over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 4 days. 0 0.50 1 1.5 2 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 4
Enalaprilat modeled serum levels with a loading dose of 3.2 mg, then 1.3 mg custom (shown daily) The first dose is larger so levels approach steady state faster. 0 0.50 1 1.5 2 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule

Maintenance schedule: 1.3 mg custom (shown daily) (iv).

Loading schedule: 3.2 mg on day 1, then 1.3 mg custom (shown daily) — reaching therapeutic levels sooner.

Modeled steady state after ~4 days: peak ≈ 1.6 mg, trough ≈ 0.99 mg body load. Population-based estimate over 15 days for a 1.3 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
ACE Inhibitor
Route modeled
IV
Model confidence
inferred
Half-life
35 h
Common dose
1.3 mg
Suggested maximum
5 mg/day
Reference dose range
0.63–5 mg (single dose)
Suggested cadence
custom (shown daily)
Validated against
1.3 mg iv — Cmax 0.10 mg/L at 0.25 h

Documented interactions

  • watch
    Enalapril (Vasotec) + Enalaprilat Stacked effects

    Enalapril (Vasotec) and Enalaprilat both push the ace in the same direction.

  • watch
    Garlic Extract (Allium sativum) + Enalaprilat Stacked effects

    Enalaprilat and Garlic Extract (Allium sativum) both push the ace in the same direction.

  • watch
    Lisinopril + Enalaprilat Stacked effects

    Enalaprilat and Lisinopril both push the ace in the same direction.

  • watch
    Ramipril + Enalaprilat Stacked effects

    Enalaprilat and Ramipril both push the ace in the same direction.

Serum checks 5 modeled interaction pairings for enalaprilat across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.