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Garlic Extract (Allium sativum)

Herboral · inferred

Aged or standardized garlic extract with allicin content. Mild antiplatelet effects due to thiosulfinates.

Projected serum levels — 600 mg, once daily

Garlic Extract (Allium sativum)
Garlic Extract (Allium sativum) modeled serum levels, 600 mg once daily over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 1 days. 0 62.5 125 188 250 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 1

Maintenance schedule: 600 mg once daily (oral).

Modeled steady state after ~1 days: peak ≈ 223 mg, trough ≈ 0.042 mg body load. Population-based estimate over 15 days for a 600 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Herb
Route modeled
Oral
Model confidence
inferred
Half-life
1.8 h
Common dose
600 mg
Suggested maximum
1.2k mg/day
Reference dose range
300–1.2k mg (single dose)
Suggested cadence
once daily

Documented interactions

  • moderate
    Alfuzosin (Uroxatral) + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Alfuzosin (Uroxatral) AUC by ~0.77x

  • moderate
    Alprazolam (Xanax) + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Alprazolam (Xanax) AUC by ~0.77x

  • moderate
    Amlodipine (Norvasc) + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Amlodipine (Norvasc) AUC by ~0.77x

  • moderate
    Anastrozole (Arimidex) + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Anastrozole (Arimidex) AUC by ~0.79x

  • moderate
    Astaxanthin + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Astaxanthin AUC by ~0.77x

  • moderate
    Atogepant (Qulipta) + Garlic Extract (Allium sativum) CYP induction

    Garlic Extract (Allium sativum) inducer of CYP3A4 predicted to change Atogepant (Qulipta) AUC by ~0.77x

Serum checks 153 modeled interaction pairings for garlic extract (allium sativum) across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.

Research behind this entry

  1. Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods Lawson LD et al. · Nutrients, 2021 DOI

    Comprehensive pharmacokinetic bioavailability study.

  2. Composition, Stability, and Bioavailability of Garlic Products Being Used in a Clinical Trial Lawson LD et al. · Journal of Agricultural and Food Chemistry, 2005 DOI

    Clinical characterization of allicin bioavailability.

  3. Effect of Cooking on Garlic (Allium sativum L.) Antiplatelet Activity and Thiosulfinates Content Banerjee SK et al. · Journal of Agricultural and Food Chemistry, 2007 DOI

    Antiplatelet mechanism study.

3 published studies referenced in the app, each with a plain-language summary.