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Char-grilled meats

Foodoral · inferred

Polycyclic aromatic hydrocarbons (benzo[a]pyrene et al.) from flame-grilling activate AhR and induce CYP1A2 ~1.5× over weeks. Similar direction to cruciferous vegetables but different ligand class. Confidence: moderate.

Projected serum levels — 1 serving (≈ 1 mg), as needed (shown daily)

Char-grilled meats
Char-grilled meats modeled serum levels, 1 serving (≈ 1 mg) as needed (shown daily) over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 7 days. 0 0.25 0.50 0.75 1 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 7

Maintenance schedule: 1 serving (≈ 1 mg) as needed (shown daily) (oral).

Modeled steady state after ~7 days: peak ≈ 0 mg, trough ≈ 0 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Food
Route modeled
Oral
Model confidence
inferred
Common dose
1 serving (≈ 1 mg)
Suggested maximum
3 serving/day
Reference dose range
1–3 serving (single dose)
Suggested cadence
as needed (shown daily)

Documented interactions

  • moderate
    Caffeine + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Caffeine AUC by ~0.68x

  • moderate
    Ciprofloxacin (Cipro) + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Ciprofloxacin (Cipro) AUC by ~0.73x

  • moderate
    Clozapine (Clozaril) + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Clozapine (Clozaril) AUC by ~0.74x

  • moderate
    Duloxetine (Cymbalta) + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Duloxetine (Cymbalta) AUC by ~0.77x

  • moderate
    Huperzine A + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Huperzine A AUC by ~0.75x

  • moderate
    Melatonin + Char-grilled meats CYP induction

    Char-grilled meats inducer of CYP1A2 predicted to change Melatonin AUC by ~0.68x

Serum checks 29 modeled interaction pairings for char-grilled meats across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.