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Vitamin B6 (Pyridoxine)

Vitaminoral · inferred

Involved in over 100 enzyme reactions, particularly amino acid metabolism, neurotransmitter synthesis, and hemoglobin production.

Projected serum levels — 50 mg, once daily

Vitamin B6 (Pyridoxine)
Vitamin B6 (Pyridoxine) modeled serum levels, 50 mg once daily over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 2 days. 0 25 50 75 100 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 2
Vitamin B6 (Pyridoxine) modeled serum levels with a loading dose of 74.3 mg, then 50 mg once daily The first dose is larger so levels approach steady state faster. 0 25 50 75 100 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule

Maintenance schedule: 50 mg once daily (oral).

Loading schedule: 74.3 mg on day 1, then 50 mg once daily — reaching therapeutic levels sooner.

Modeled steady state after ~2 days: peak ≈ 52.0 mg, trough ≈ 18.6 mg body load. Population-based estimate over 15 days for a 50 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Vitamin
Route modeled
Oral
Model confidence
inferred
Half-life
15 h
Common dose
50 mg
Suggested maximum
100 mg/day
Reference dose range
25–100 mg (single dose)
Suggested cadence
once daily
Validated against
40 mg oral — Cmax 0.20 mg/L at 1.5 h

Documented interactions

Serum checks 3 modeled interaction pairings for vitamin b6 (pyridoxine) across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.

Research behind this entry

  1. Vitamin B6 and its role in cell metabolism and physiology Mooney S et al. · Molecules, 2009 DOI

    Comprehensive review of vitamin B6 biochemistry showing its involvement in over 140 enzymatic reactions essential for amino acid, glucose, and lipid metabolism.

  2. A systematic review and meta-analysis of B vitamin supplementation on depressive symptoms, anxiety, and stress Young LM et al. · Nutrients, 2019 DOI

    Meta-analysis found B vitamin supplementation, particularly B6, had a small but significant beneficial effect on stress and mood in healthy and at-risk populations.

  3. Vitamin B6 supplementation increases immune responses in critically ill patients Cheng CH et al. · European Journal of Clinical Nutrition, 2006 DOI

    RCT in ICU patients demonstrated that B6 supplementation significantly improved immune cell counts and responsiveness compared to control.

  4. Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial. Pouteau E, Kabir-Ahmadi M, Noah L, Mazur A, Dye L, Hellhammer J, Pickering G, Dubray C · PloS one, 2018 DOI

    This citation reports a human clinical study involving a formulation related to Vitamin B6 (Pyridoxine), not the isolated identity. The randomized trial used magnesium plus vitamin B6, so vitamin-B6-specific effects…

4 published studies referenced in the app, each with a plain-language summary.