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Vitamin A (Retinol)

Vitaminoral · inferred

Fat-soluble vitamin essential for vision, immune function, and cellular communication.

Projected serum levels — 5k IU (≈ 1.5 mg), once daily

Vitamin A (Retinol)
Vitamin A (Retinol) modeled serum levels, 5k IU (≈ 1.5 mg) once daily over 121 days Population-based pharmacokinetic estimate. Steady state reached after approximately 98 days. 0 25 50 75 100 Day 0 Day 30 Day 61 Day 91 Day 121 Time on a regular schedule ≈ steady state · day 98
Vitamin A (Retinol) modeled serum levels with a loading dose of 15k IU, then 5k IU (≈ 1.5 mg) once daily The first dose is larger so levels approach steady state faster. 0 25 50 75 100 Day 0 Day 30 Day 61 Day 91 Day 121 Time on a regular schedule

Maintenance schedule: 5k IU (≈ 1.5 mg) once daily (oral).

Loading schedule: 15k IU on day 1, then 5k IU (≈ 1.5 mg) once daily — reaching therapeutic levels sooner.

Modeled steady state after ~98 days: peak ≈ 78.5 mg, trough ≈ 77.9 mg body load. Population-based estimate over 121 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Vitamin
Route modeled
Oral
Model confidence
inferred
Half-life
60 days
Common dose
5k IU (≈ 1.5 mg)
Suggested maximum
10k IU/day
Reference dose range
2.5k–10k IU (single dose)
Suggested cadence
once daily

Documented interactions

  • danger
    Levothyroxine (Synthroid) + Vitamin A (Retinol) Protein binding

    Vitamin A (Retinol) may displace Levothyroxine (Synthroid) from plasma protein binding sites, transiently raising free drug concentration. This drug has a narrow therapeutic index; free concentration…

  • warning
    Apigenin + Vitamin A (Retinol) Protein binding

    Apigenin may displace Vitamin A (Retinol) from plasma protein binding sites, transiently raising free drug concentration.

  • warning
    Aripiprazole (Abilify) + Vitamin A (Retinol) Protein binding

    Aripiprazole (Abilify) may displace Vitamin A (Retinol) from plasma protein binding sites, transiently raising free drug concentration.

  • warning
    Armour Thyroid (Desiccated Thyroid Extract) + Vitamin A (Retinol) Protein binding

    Vitamin A (Retinol) may displace Armour Thyroid (Desiccated Thyroid Extract) from plasma protein binding sites, transiently raising free drug concentration.

  • warning
    Astaxanthin + Vitamin A (Retinol) Protein binding

    Astaxanthin may displace Vitamin A (Retinol) from plasma protein binding sites, transiently raising free drug concentration.

  • warning
    Atomoxetine (Strattera) + Vitamin A (Retinol) Protein binding

    Atomoxetine (Strattera) may displace Vitamin A (Retinol) from plasma protein binding sites, transiently raising free drug concentration.

Serum checks 139 modeled interaction pairings for vitamin a (retinol) across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.

Research behind this entry

  1. Vitamin A deficiency and clinical disease: an historical overview Sommer A · Journal of Nutrition, 2008 DOI

    Landmark historical review documenting the progression from night blindness to xerophthalmia and the critical role of vitamin A in immune defense.

  2. Effects of vitamin A supplementation on immune function in elderly people Villamor E et al. · Lancet Infectious Diseases, 2005 DOI

    Review showing vitamin A modulates innate and adaptive immunity, with deficiency impairing barrier function, immune cell activity, and antibody responses.

  3. Impact of vitamin A supplementation on the incidence of infection in elderly nursing-home residents: a randomized controlled trial. Murphy S, West KP, Greenough WB, Cherot E, Katz J, Clement L · Age and ageing, 1992 DOI

    This citation reports a human clinical study involving a formulation related to Vitamin A (Retinol), not the isolated identity. The randomized study administered a vitamin A supplement; results apply to the studied…

3 published studies referenced in the app, each with a plain-language summary.