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HGH (Human Growth Hormone / Somatropin)

Peptideprescriptionsubcutaneous · inferred

Recombinant human growth hormone (somatropin), a 191-amino-acid protein identical to pituitary-derived GH. SC half-life ~3 hours (IV ~20 min). Prescribed for GH deficiency, Turner syndrome, and HIV wasting. Off-label for anti-aging and bodybuilding. Stimulates IGF-1 production, protein synthesis, lipolysis, and bone growth.

Projected serum levels — 2 IU (≈ 0.67 mg), once daily

HGH (Human Growth Hormone / Somatropin)
HGH (Human Growth Hormone / Somatropin) modeled serum levels, 2 IU (≈ 0.67 mg) once daily over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 1 days. 0 0.25 0.50 0.75 1 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 1

Maintenance schedule: 2 IU (≈ 0.67 mg) once daily (subcutaneous).

Modeled steady state after ~1 days: peak ≈ 0.15 mg, trough ≈ 0.004 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Peptide
Route modeled
Subcutaneous
Model confidence
inferred
Half-life
3 h
Common dose
2 IU (≈ 0.67 mg)
Suggested maximum
8 IU/day
Reference dose range
1–8 IU (single dose)
Suggested cadence
once daily
Validated against
2 mg sc — Cmax 0.015 mg/L at 4 h

Documented interactions

  • watch
    BPC-157 (Body Protection Compound) + HGH (Human Growth Hormone / Somatropin) Stacked effects

    BPC-157 (Body Protection Compound) and HGH (Human Growth Hormone / Somatropin) both push the growth hormone receptor in the same direction.

  • watch
    GHRP-2 (Pralmorelin) + HGH (Human Growth Hormone / Somatropin) Stacked effects

    GHRP-2 (Pralmorelin) and HGH (Human Growth Hormone / Somatropin) both push the growth hormone receptor in the same direction.

  • watch
    GHRP-6 + HGH (Human Growth Hormone / Somatropin) Stacked effects

    GHRP-6 and HGH (Human Growth Hormone / Somatropin) both push the growth hormone receptor in the same direction.

Serum checks 3 modeled interaction pairings for hgh (human growth hormone / somatropin) across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.

Research behind this entry

  1. Pharmacokinetics of human growth hormone administered subcutaneously with two different injection systems de la Motte S et al. · Hormone Research in Paediatrics, 2001 DOI

    PK study comparing injection systems showing SC somatropin half-life of ~248 min (4.1 h), Tmax of 3.5-6 h, and bioequivalence between pen and vial/syringe delivery methods.

  2. Developments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes Hoybye C et al. · International Journal of Pharmaceutical Investigation, 2014 DOI

    Review of GH pharmacokinetics (SC half-life ~3 h) and development of long-acting formulations, PEGylation strategies, and alternative delivery routes to reduce injection frequency.

  3. Pharmacokinetics and short-term metabolic effects of mammalian cell-derived biosynthetic human growth hormone in man Zeisel HJ et al. · Hormone Research, 1992 DOI

    Established basic PK parameters of recombinant somatropin showing dose-proportional pharmacokinetics, SC Tmax of 3-6 hours, and metabolic effects including increased FFA and decreased urea nitrogen.

3 published studies referenced in the app, each with a plain-language summary.