Boron

Mineraloral · inferred

Trace mineral that supports bone health, testosterone metabolism, and cognitive function. Readily absorbed and excreted renally with a 21-hour half-life.

Projected serum levels — 3 mg, once daily

Boron
Boron modeled serum levels, 3 mg once daily over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 2 days. 0 1.3 2.5 3.8 5 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 2
Boron modeled serum levels with a loading dose of 5.4 mg, then 3 mg once daily The first dose is larger so levels approach steady state faster. 0 1.3 2.5 3.8 5 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule

Maintenance schedule: 3 mg once daily (oral).

Loading schedule: 5.4 mg on day 1, then 3 mg once daily — reaching therapeutic levels sooner.

Modeled steady state after ~2 days: peak ≈ 4.6 mg, trough ≈ 2.2 mg body load. Population-based estimate over 15 days for a 3 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Mineral
Route modeled
Oral
Model confidence
inferred
Half-life
21 h
Common dose
3 mg
Suggested maximum
20 mg/day
Reference dose range
1.5–20 mg (single dose)
Suggested cadence
once daily

Documented interactions

  • caution
    Alendronate (Fosamax) + Boron Chelation

    Alendronate (Fosamax) (bisphosphonate) forms insoluble complexes with Boron in the GI tract, reducing absorption of both.

  • caution
    Armour Thyroid (Desiccated Thyroid Extract) + Boron Chelation

    Armour Thyroid (Desiccated Thyroid Extract) (thyroid hormone) forms insoluble complexes with Boron in the GI tract, reducing absorption of both.

Serum checks 2 modeled interaction pairings for boron across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.

Research behind this entry

  1. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines Naghii MR et al. · Journal of Trace Elements in Medicine and Biology, 2011 DOI

    Study found that 10 mg/day boron supplementation for one week significantly increased free testosterone by 28% and reduced estradiol and inflammatory markers.

  2. Nothing boring about boron Pizzorno L · Integrative Medicine, 2015 DOI

    Comprehensive review of boron roles in bone health, wound healing, hormone metabolism, and cognitive function, noting widespread dietary insufficiency.

2 published studies referenced in the app, each with a plain-language summary.