Zinc Carnosine (Polaprezinc)

Gastrointestinal Zinc Complex

Zinc carnosine, or polaprezinc, is a defined zinc-L-carnosine complex. Product mass is not elemental-zinc mass. Chronic excess zinc can cause copper deficiency, and evidence for gut protection does not establish broad immune or exercise-recovery benefits.

Pharmacokinetic model

A route-level PK model for zinc carnosine (polaprezinc) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Gastrointestinal Zinc Complex
Suggested cadence
once daily

Research behind this entry

  1. Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes Mahmood A, FitzGerald AJ, Marchbank T, Ntatsaki E, Murray D, Ghosh S, Playford RJ · Gut, 2007 DOI

    Cell and animal experiments were paired with a randomized crossover study in ten healthy volunteers. Zinc carnosine prevented the permeability rise seen during five days of high-dose indomethacin, but the tiny challenge…

1 published study referenced in the app, each with a plain-language summary.