Wild Yam

Herb

Products derived from Dioscorea species and marketed mainly for menopausal or hormone-related claims. Diosgenin is a laboratory precursor used in steroid manufacture, but a controlled human trial did not show that a wild yam cream changed measured sex hormones or outperformed placebo for menopausal symptoms.

Pharmacokinetic model

A route-level PK model for wild yam is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women Komesaroff PA, Black CV, Cable V, Sudhir K · Climacteric, 2001

    Double-blind placebo-controlled crossover study in 23 menopausal women compared an active wild yam cream with matching placebo for three months each. The active cream did not significantly outperform placebo for…

1 published study referenced in the app, each with a plain-language summary.