Vitamin B Complex

Multi-Vitamin

Supplement category combining thiamine, riboflavin, niacin, pantothenic acid, vitamin B6, biotin, folate, and vitamin B12 in product-specific forms and doses. Benefits depend on the formulation and baseline nutrient status; high-dose products are not interchangeable, and chronic excess vitamin B6 can cause peripheral neuropathy.

Pharmacokinetic model

A route-level PK model for vitamin b complex is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Multi-Vitamin
Suggested cadence
once daily

Research behind this entry

  1. B Vitamins: Functions and Uses in Medicine Hanna M, Jaqua E, Nguyen V, Clay J · Permanente Journal, 2022 DOI

    Narrative clinical review outlines the distinct cofactor functions, deficiency states, dietary sources, and medical uses of the eight B vitamin groups. It is background evidence, not a trial of one standardized…

  2. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and At-Risk Individuals Young LM, Pipingas A, White DJ, Gauci S, Scholey A · Nutrients, 2019 DOI

    Review of 16 randomized trials involving 2,015 participants found a small pooled improvement in stress, but no significant effect on depressive symptoms or anxiety. Formulations varied and included at least three B…

  3. A functional evaluation of anti-fatigue and exercise performance improvement following vitamin B complex supplementation in healthy humans, a randomized double-blind trial. Lee MC, Hsu YJ, Shen SY, Ho CS, Huang CC · International journal of medical sciences, 2023 DOI

    This citation reports a human clinical study involving Vitamin B Complex. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.