VIP Peptide
Peptide
Vasoactive intestinal peptide is an endogenous neuropeptide involved in vascular, gastrointestinal, and immune signaling. Exogenous human work includes experimental IV migraine provocation; it does not establish VIP as a general therapeutic supplement.
Pharmacokinetic model
A route-level PK model for vip peptide is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Peptide
- Suggested cadence
- once daily
Research behind this entry
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Effect of Vasoactive Intestinal Polypeptide on Development of Migraine Headaches: A Randomized Clinical Trial
Randomized crossover provocation study found that a two-hour VIP infusion induced migraine attacks in 15 of 21 participants versus 1 after placebo. It identifies a migraine pathway and potential drug target, not a…
1 published study referenced in the app, each with a plain-language summary.