Ursodeoxycholic Acid (UDCA)
Bile Acid Medicationprescription
UDCA is a prescription hydrophilic bile acid used in cholestatic disease. Parent, glycine conjugate, and taurine conjugate circulate through enterohepatic cycling.
Pharmacokinetic model
A route-level PK model for ursodeoxycholic acid (udca) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Bile Acid Medication
- Suggested cadence
- once daily
Research behind this entry
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Pharmacokinetics of Ursodeoxycholic Acid in Elderly Volunteers Compared With Younger Adults in a Korean Population
Sixteen elderly and sixteen younger adults received single and repeated UDCA. Elderly exposure was two- to four-fold higher and parent plus conjugates showed multiple peaks, demonstrating that a simple universal curve…
1 published study referenced in the app, each with a plain-language summary.