Tocotrienols

Vitamin E Family

Tocotrienols are four unsaturated vitamin E homologues distinct from the tocopherols. Evidence from one mixed palm or annatto preparation does not transfer to another composition or to isolated homologues.

Pharmacokinetic model

A route-level PK model for tocotrienols is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Vitamin E Family
Suggested cadence
once daily

Research behind this entry

  1. Clinical investigation of the protective effects of palm vitamin E tocotrienols on brain white matter Gopalan Y, Shuaib IL, Magosso E, Ansari MA, Abu Bakar MR, Wong JW, Khan NA, Liong WC, Sundram K, Ng BH, Karuthan C, Yuen KH · Stroke, 2014 DOI

    In 121 adults with cardiovascular risk factors and MRI white-matter lesions, a specific mixed palm-tocotrienol product or placebo was given for two years. Lesion volume progressed less in the active group at two years;…

1 published study referenced in the app, each with a plain-language summary.