Stinging Nettle

Herb

Urtica dioica is consumed as food and sold as leaf, root, seed, and concentrated products. The literature spans nutritional composition, preclinical pharmacology, preparation-specific uses, and adverse case reports; evidence should not be generalized across plant parts.

Pharmacokinetic model

A route-level PK model for stinging nettle is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. Nutritional and pharmacological importance of stinging nettle (Urtica dioica L.): A review Bhusal KK, Magar SK, Thapa R, Lamsal A, Bhandari S, Maharjan R, Shrestha S, Shrestha J · Heliyon, 2022 DOI

    Broad narrative review of the plant's nutritional composition, traditional uses, and mostly preclinical pharmacology. The verified record is PMID 35800714.

  2. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ · American Journal of Case Reports, 2021 DOI

    Single case report describing galactorrhea temporally associated with stinging-nettle use. It is a safety signal, not proof of frequency, mechanism, or efficacy.

  3. Comparative Effects of Premedication with Ibuprofen and Essential Oil of Urtica Dioica on Post-Endodontic Pain: Clinical Trial. Elahinia P, Vali Sichani A, Vali Sichani A, Yaraghi N, Yegdaneh A, Khosravani Z · Journal of dentistry (Shiraz, Iran), 2024 DOI

    This citation reports a human primary study involving a formulation related to Stinging Nettle, not the isolated identity. The clinical trial used Urtica dioica essential oil in a procedural setting; it is not evidence…

3 published studies referenced in the app, each with a plain-language summary.