Souvenaid

Medical Food

Oral medical food containing the Fortasyn Connect multi-nutrient formulation and marketed for use under medical supervision in people with early Alzheimer's disease. Randomized-trial synthesis has not shown a convincing effect on progression to dementia or most patient-important cognitive and functional outcomes.

Pharmacokinetic model

A route-level PK model for souvenaid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Medical Food
Suggested cadence
once daily

Research behind this entry

  1. Souvenaid for Alzheimer's disease Burckhardt M, Watzke S, Wienke A, Langer G, Fink A · Cochrane Database of Systematic Reviews, 2020 DOI

    Cochrane review included three randomized placebo-controlled trials with 1,097 participants. Moderate-certainty evidence found little or no effect on progression to dementia, cognition, or everyday function; a small…

  2. The effects of omega-3, DHA, EPA, Souvenaid in Alzheimer's disease: A systematic review and meta-analysis Calderon Martinez E, Saji SZ, Salazar Ore JV, Borges-Sosa OA, Srinivas S, Mareddy NSR, Manzoor T, Di Vanna M, Al Shanableh Y, Taneja R, Arruarana VS · Neuropsychopharmacology Reports, 2024 DOI

    Review pooled 14 heterogeneous studies of several omega-3 interventions and Souvenaid. It reported less decline on the CDR scale, but no significant differences for MMSE, ADAS-cog, activities of daily living, adverse…

  3. Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial. Scheltens P, Twisk JW, Blesa R, Scarpini E, von Arnim CA, Bongers A, Harrison J, Swinkels SH, Stam CJ, de Waal H, Wurtman RJ, Wieggers RL, Vellas B, Kamphuis PJ · Journal of Alzheimer's disease : JAD, 2012 DOI

    This citation reports a human clinical study involving Souvenaid. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.