Sodium Butyrate
Sodium salt of butyric acid used experimentally and sold as a supplement. The retained studies concern mouse or rat disease models, not controlled human efficacy or supplement pharmacokinetics.
Pharmacokinetic model
A route-level PK model for sodium butyrate is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Short-Chain Fatty Acid Salt
- Suggested cadence
- once daily
Research behind this entry
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Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning
Mouse high-fat-diet experiment reported metabolic and epigenetic changes after sodium butyrate. It does not establish weight-loss or insulin- sensitivity benefits in humans.
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Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression
Mouse Alzheimer-model study reported memory changes with sodium butyrate. It is preclinical and does not show prevention or treatment of human dementia.
2 published studies referenced in the app, each with a plain-language summary.