SkQ1

Mitochondria-Targeted Research Compoundprescription

SkQ1 is a plastoquinone-containing mitochondria-targeted compound clinically studied as an eye drop. Other routes are experimental and must not inherit ophthalmic evidence.

Pharmacokinetic model

A route-level PK model for skq1 is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Mitochondria-Targeted Research Compound
Suggested cadence
once daily

Research behind this entry

  1. SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study Petrov A, Perekhvatova N, Skulachev M, Stein L, Ousler G · Advances in Therapy, 2016 DOI

    Ninety-one participants with dry eye used 0.155 or 1.55 mcg/mL SkQ1 ophthalmic solution or placebo for 29 days. The study was local and did not report systemic pharmacokinetics.

1 published study referenced in the app, each with a plain-language summary.