Sermorelin

Peptideprescription

Synthetic growth hormone-releasing hormone fragment historically used in pediatric diagnostic and treatment contexts. Adult anti-aging and body- composition marketing is not established by the profile's cited studies.

Pharmacokinetic model

A route-level PK model for sermorelin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Peptide
Suggested cadence
once daily

Research behind this entry

  1. GHRH and sleep Obal F Jr, Krueger JM · Sleep Medicine Reviews, 2004 DOI

    Review of endogenous and exogenous GHRH in sleep regulation. It is not a sermorelin-specific efficacy trial, so it cannot support claims that sermorelin reliably improves sleep. This is the only plausibly relevant…

  2. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency Prakash A, Goa KL · BioDrugs, 1999 DOI

    Review of historical pediatric diagnostic and treatment use. It does not establish contemporary off-label anti-aging or body-composition benefits in adults.

  3. Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women. Khorram O, Laughlin GA, Yen SS · The Journal of clinical endocrinology and metabolism, 1997 DOI

    This citation reports a human clinical study involving analogue or class evidence, not direct identity-level evidence for Sermorelin. The trial used a modified GHRH(1-29) analogue rather than identity-confirmed…

3 published studies referenced in the app, each with a plain-language summary.