Sarcosine
Sarcosine, or N-methylglycine, is an endogenous glycine derivative and glycine-transporter-1 inhibitor studied experimentally in psychiatric disorders. Small diagnosis-specific trials do not establish it as a general nootropic or define routine self-treatment.
Pharmacokinetic model
A route-level PK model for sarcosine is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Amino Acid Derivative
- Suggested cadence
- once daily
Research behind this entry
-
Sarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind study
Twenty acutely ill, drug-free participants received 1 or 2 g/day for six weeks. Response was more frequent at 2 g, especially among antipsychotic- naive participants, but the dose-by-time comparison was not significant…
1 published study referenced in the app, each with a plain-language summary.