Rutin

Flavonoid Glycoside

Rutin is quercetin-3-O-rutinoside, a glycosylated flavonoid found in many foods. It is chemically distinct from quercetin, and product formulation plus gut-microbial metabolism materially affect exposure.

Pharmacokinetic model

A route-level PK model for rutin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Flavonoid Glycoside
Suggested cadence
once daily

Research behind this entry

  1. Bioavailability and efficiency of rutin as an antioxidant: a human supplementation study Boyle SP, Dobson VL, Duthie SJ, Hinselwood DC, Kyle JA, Collins AR · European Journal of Clinical Nutrition, 2000 DOI

    Eighteen healthy women completed a placebo-controlled 500 mg/day, six-week rutin supplementation study with an acute pharmacokinetic phase. Plasma flavonoid exposure increased, but measured antioxidant-status outcomes…

1 published study referenced in the app, each with a plain-language summary.