Protease

Digestive Enzyme

Protease supplements may contain fungal, bacterial, pancreatic, papaya, or pineapple enzymes with different activity assays. They cannot be represented as one chemical identity.

Pharmacokinetic model

A route-level PK model for protease is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Digestive Enzyme
Suggested cadence
once daily

Research behind this entry

  1. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study Delgarm P, Mokhtare M, Ebrahimi Daryani N, Abolghasemi J, Rahideh ST · Scientific Reports, 2025 DOI

    Seventy participants received 400 mg/day bromelain or placebo for eight weeks. Bromelain is one defined proteolytic preparation; its outcome data cannot be assigned to the generic protease class and no intact-enzyme…

1 published study referenced in the app, each with a plain-language summary.