Propionyl-L-Carnitine
Carnitine Derivative
Propionyl-L-carnitine is an acylcarnitine that interconverts with regulated endogenous carnitine pools. Salt form and route affect dose interpretation.
Pharmacokinetic model
A route-level PK model for propionyl-l-carnitine is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Carnitine Derivative
- Suggested cadence
- once daily
Research behind this entry
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Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption
Healthy men received 1 to 8 g IV propionyl-L-carnitine hydrochloride. Elimination was rapid, renal clearance increased with dose, and L-carnitine was a major metabolite, demonstrating nonlinear endogenous-pool handling.
1 published study referenced in the app, each with a plain-language summary.