Pomegranate Extract

Supplement

Punica granatum fruit products studied for cardiovascular, cognitive, and cancer-related outcomes. Human findings are limited and preparation-specific; some biomarker changes have not translated into established clinical benefits.

Pharmacokinetic model

A route-level PK model for pomegranate extract is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Supplement
Suggested cadence
once daily

Research behind this entry

  1. Impact of Pomegranate Extract Supplementation on Physical and Cognitive Function in Community-Dwelling Older Adults Aged 55-70 Years: A Randomised Double-Blind Clinical Trial Farhat G, Malla J, Al-Dujaili EAS, Vadher J, Nayak P, Drinkwater K · Geriatrics, 2025 DOI

    Eighty-six adults received 740 mg/day extract or placebo for 12 weeks. One reasoning outcome improved, several outcomes only trended, and physical function did not differ. PMID 39997528 is the verified record.

  2. A review of pomegranate in prostate cancer Paller CJ, Pantuck A, Carducci MA · Prostate Cancer and Prostatic Diseases, 2017 DOI

    Review of laboratory and early clinical prostate-cancer research. It describes exploratory biomarker findings but does not establish pomegranate extract as a cancer treatment.

2 published studies referenced in the app, each with a plain-language summary.