Peppermint Oil

Botanical Essential Oil

Peppermint oil contains menthol, menthone, and other volatile constituents. Enteric-coated IBS products differ from food flavoring, aromatherapy, and undiluted essential oil; swallowing concentrated essential oil can be hazardous.

Pharmacokinetic model

A route-level PK model for peppermint oil is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Botanical Essential Oil
Suggested cadence
once daily

Research behind this entry

  1. Peppermint Oil Treatment for Irritable Bowel Syndrome: A Randomized Placebo-Controlled Trial Nee J, Ballou S, Kelley JM, Kaptchuk TJ, Hirsch W, Katon J, Cheng V, Rangan V, Lembo A, Iturrino J · American Journal of Gastroenterology, 2021 DOI

    Adults with moderate-to-severe IBS received enteric-coated peppermint oil 180 mg three times daily or placebo for six weeks. Symptom improvement did not differ between groups on the primary or secondary measures,…

1 published study referenced in the app, each with a plain-language summary.