Pantothenic Acid (Vitamin B5)
Water-soluble vitamin essential for coenzyme A synthesis, involved in energy metabolism and fatty acid synthesis.
Projected serum levels — 500 mg, once daily
Maintenance schedule: 500 mg once daily (oral).
Loading schedule: 1.5k mg on day 1, then 500 mg once daily — reaching therapeutic levels sooner.
Modeled steady state after ~11 days: peak ≈ 2.2k mg, trough ≈ 1.9k mg body load. Population-based estimate over 33 days for a 500 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Vitamin
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 4.2 days
- Common dose
- 500 mg
- Suggested maximum
- 1k mg/day
- Reference dose range
- 250–1k mg (single dose)
- Suggested cadence
- once daily
Research behind this entry
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A randomized, double-blind, placebo-controlled study to evaluate the efficacy of a pantothenic acid based dietary supplement on skin health in adults
RCT found pantothenic acid supplementation significantly reduced facial acne lesions by 67% over 12 weeks compared to placebo.
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Pantothenic acid and its derivatives in wound healing
Review showing dexpanthenol (provitamin B5) accelerates wound healing, stimulates fibroblast proliferation, and improves skin barrier function.
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Dexpanthenol: an overview of its pharmacology and potential role in dermatological practice
Comprehensive review of pantothenic acid derivatives showing benefits for skin hydration, wound healing, and anti-inflammatory effects in dermatological conditions.
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A randomized, double-blind, placebo-controlled study of a novel pantothenic Acid-based dietary supplement in subjects with mild to moderate facial acne.
This citation reports a human primary study involving a formulation related to Pantothenic Acid (Vitamin B5), not the isolated identity. The randomized trial used a pantothenic-acid-based dietary supplement, so isolated…
4 published studies referenced in the app, each with a plain-language summary.