Oleuropein

Olive Secoiridoid

Oleuropein is an olive glycoside converted during digestion and metabolism to products including hydroxytyrosol. Olive leaf extracts and purified oleuropein are not interchangeable.

Pharmacokinetic model

A route-level PK model for oleuropein is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category: Olive Secoiridoid
Suggested cadence: once daily

Research behind this entry

Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects Carnevale R, Silvestri R, Loffredo L, Novo M, Cammisotto V, Castellani V, Bartimoccia S, Nocella C, Violi F · British Journal of Clinical Pharmacology, 2018 DOI
Twenty healthy adults received 20 mg oleuropein or placebo with a meal. The study measured postprandial metabolic outcomes and supports an acute product-specific effect, not a validated parent serum model.

1 published study referenced in the app, each with a plain-language summary.