Oleic Acid

Fatty Acid

Oleic acid is a common monounsaturated fatty acid in foods and human lipid pools. Dietary substitution studies do not isolate a drug-like serum concentration.

Pharmacokinetic model

A route-level PK model for oleic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Fatty Acid
Suggested cadence
once daily

Research behind this entry

  1. Comparison of diets enriched in stearic, oleic, and palmitic acids on inflammation, immune response, cardiometabolic risk factors, and fecal bile acid concentrations in mildly hypercholesterolemic postmenopausal women Meng H, Matthan NR, Wu D, Li L, Rodríguez-Morató J, Cohen R, Galluccio JM, Dolnikowski GG, Lichtenstein AH · American Journal of Clinical Nutrition, 2019 DOI

    A controlled randomized crossover compared whole diets enriched in oleic, stearic, or palmitic acid. It informs dietary substitution outcomes but does not support a drug-like oleic-acid serum curve.

1 published study referenced in the app, each with a plain-language summary.