N-Acetyl-L-Tyrosine (NALT)

Acetylated Amino Acid

NALT is a water-soluble acetylated tyrosine derivative. Solubility is not proof of superior oral bioavailability: intravenous studies show substantial unchanged urinary loss, and no controlled human evidence validates marketed focus or mood claims.

Pharmacokinetic model

A route-level PK model for n-acetyl-l-tyrosine (nalt) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Acetylated Amino Acid
Suggested cadence
once daily

Research behind this entry

  1. N-acetyl-L-tyrosine as a tyrosine source in adult parenteral nutrition Hoffer LJ, Sher K, Saboohi F, Bernier P, MacNamara EM, Rinzler D · JPEN Journal of Parenteral and Enteral Nutrition, 2003 DOI

    In 13 adults receiving continuous parenteral nutrition, about 35% of administered NALT was excreted unchanged in urine. This direct human study concerns intravenous nutritional use and gives no support to claims of…

1 published study referenced in the app, each with a plain-language summary.