N-Acetylglucosamine

Amino Sugar

N-acetylglucosamine (GlcNAc or NAG) is an endogenous amino sugar used in glycoconjugate synthesis. It is distinct from glucosamine hydrochloride and glucosamine sulfate. Online anxiety claims are not supported by the retained clinical evidence.

Pharmacokinetic model

A route-level PK model for n-acetylglucosamine is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Amino Sugar
Suggested cadence
once daily

Research behind this entry

  1. A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease Salvatore S, Heuschkel R, Tomlin S, Davies SE, Edwards S, Walker-Smith JA, French I, Murch SH · Alimentary Pharmacology & Therapeutics, 2000 DOI

    Twelve children received oral GlcNAc as adjunct therapy and nine received rectal GlcNAc for severe treatment-resistant inflammatory bowel disease. Some improved, but the uncontrolled pilot explicitly called for…

1 published study referenced in the app, each with a plain-language summary.