Mycophenolic Acid
Active species of mycophenolate mofetil after hepatic esterase hydrolysis. IMPDH inhibitor selectively depleting GTP in lymphocytes. Exhibits enterohepatic recirculation producing a secondary peak at 6-12 h.
Projected serum levels — 720 mg, twice daily
Maintenance schedule: 720 mg twice daily (oral).
Modeled steady state after ~1 days: peak ≈ 189 mg, trough ≈ 0.000 mg body load. Population-based estimate over 15 days for a 720 mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Immunosuppressant metabolite
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 12 h
- Common dose
- 720 mg
- Suggested maximum
- 1.4k mg/day
- Reference dose range
- 180–1.4k mg (single dose)
- Suggested cadence
- twice daily
- Validated against
- 720 mg oral — Cmax 24 mg/L at 2 h
Documented interactions
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watch
Mycophenolate Mofetil (CellCept) + Mycophenolic Acid
Mycophenolate Mofetil (CellCept) and Mycophenolic Acid both push the impdh in the same direction.
Serum checks 1 modeled interaction pairings for mycophenolic acid across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.