Mucuna Pruriens
Velvet-bean seed preparations naturally containing levodopa alongside other plant constituents. Small Parkinson disease trials demonstrate that defined preparations can deliver pharmacologically meaningful levodopa, but commercial products are not compositionally interchangeable.
Pharmacokinetic model
A route-level PK model for mucuna pruriens is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study
Eight patients completed a randomized double-blind crossover comparison of standard levodopa/carbidopa with 15 g and 30 g of an analyzed Mucuna preparation. The 30 g preparation produced faster onset, higher levodopa…
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Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis
Prospective study compared 75 fertile controls with 75 men undergoing infertility evaluation and reported changes in semen, catecholamine, and reproductive-hormone measures after Mucuna treatment. The design was not a…
2 published studies referenced in the app, each with a plain-language summary.