MitoQ

Mitochondria-Targeted Compound

MitoQ is a triphenylphosphonium-linked ubiquinone designed to accumulate in mitochondria. Small human trials have measured selected vascular and exercise outcomes, but results remain indication-specific and should not be generalized to anti-aging or disease-treatment claims.

Pharmacokinetic model

A route-level PK model for mitoq is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Mitochondria-Targeted Compound
Suggested cadence
once daily

Research behind this entry

  1. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP, Seals DR · Hypertension, 2018 DOI

    Twenty older adults completed a six-week randomized, double-blind crossover trial of 20 mg/day. Flow-mediated dilation improved and plasma MitoQ was detectable, but several vascular findings came from small subgroups;…

1 published study referenced in the app, each with a plain-language summary.