Melanotan 1
Synthetic alpha-MSH analogue also known as NDP-MSH or afamelanotide. Controlled clinical research and the approved implant must not be conflated with unregulated daily-injection products sold as Melanotan I.
Pharmacokinetic model
A route-level PK model for melanotan 1 is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Peptide
- Suggested cadence
- once daily
Research behind this entry
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Effect of MELANOTAN, [Nle4, D-Phe7]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles
Placebo-controlled study in 77 white participants found increased melanin density after the studied Melanotan preparation, including among several MC1R variant groups. It does not validate grey-market product purity or…
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An unhealthy glow? A review of melanotan use and associated clinical outcomes
Review catalogued reported tanning effects and adverse clinical outcomes for Melanotan I and II, while emphasizing weak reporting and unknown long-term toxicology. It cannot assign events reliably to a verified…
2 published studies referenced in the app, each with a plain-language summary.