Matrine
Quinolozidine Alkaloid
Matrine is an alkaloid found in Sophora species. Isolated matrine, Sophora extracts, oxymatrine, and multi-herb products are distinct interventions; evidence for one must not be assigned to the others.
Pharmacokinetic model
A route-level PK model for matrine is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Quinolozidine Alkaloid
- Suggested cadence
- once daily
Research behind this entry
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Pharmacokinetic Basis for Using Saliva Matrine Concentrations as a Clinical Compliance Monitoring in Antitumor B Chemoprevention Trials in Humans
Eight healthy volunteers received 2,400 mg of a multi-component Antitumor B botanical tablet. Matrine was quantified in plasma and saliva, with roughly 10-hour plasma half-life and high saliva-to-plasma ratios; these…
1 published study referenced in the app, each with a plain-language summary.