Malic Acid
Organic Acid Supplement
Malic acid is the protonated form of malate, an endogenous citric-acid-cycle intermediate and common food acid. Salt form, stereochemistry, endogenous production, and coformulated magnesium all matter when interpreting a product.
Pharmacokinetic model
A route-level PK model for malic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Organic Acid Supplement
- Suggested cadence
- once daily
Research behind this entry
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Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study
Twenty-four fibromyalgia patients tested tablets containing both 200 mg malic acid and 50 mg magnesium. The blinded fixed-dose phase showed no clear benefit; apparent improvement during later dose escalation was…
1 published study referenced in the app, each with a plain-language summary.