Maitake
Grifola frondosa mushroom consumed as food or concentrated extracts. Reviews describe extensive preclinical work, but systematic human evidence for safety and effectiveness is sparse and preparation-specific.
Pharmacokinetic model
A route-level PK model for maitake is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Supplement
- Suggested cadence
- once daily
Research behind this entry
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Bioactive Ingredients and Medicinal Values of Grifola frondosa (Maitake)
Narrative review catalogued polysaccharides, proteins, small molecules, and predominantly preclinical findings. It does not establish clinical efficacy for a generic mushroom powder or extract.
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Maitake mushroom (Grifola frondosa): systematic review by the natural standard research collaboration
Evidence-based review concluded that systematic human study of maitake safety and effectiveness was lacking and called for randomized controlled trials despite popular commercial use.
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Effect of Maitake D-fraction in advanced laryngeal and pharyngeal cancers during concurrent chemoradiotherapy: A randomized clinical trial.
This citation reports a human clinical study involving Maitake. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
3 published studies referenced in the app, each with a plain-language summary.