L-Lysine
Essential cationic amino acid required for protein synthesis and involved in collagen, carnitine, and lysine-derived metabolite pathways. Claims for herpes prevention are based on mixed and indication-specific evidence; this entry does not treat lysine exposure as proof of antiviral efficacy.
Projected serum levels — 1k mg, once daily
Maintenance schedule: 1k mg once daily (oral).
Modeled steady state after ~1 days: peak ≈ 297 mg, trough ≈ 0.13 mg body load. Population-based estimate over 15 days for a 1k mg dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Amino Acid
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 1.8 h
- Common dose
- 1k mg
- Suggested maximum
- 6k mg/day
- Reference dose range
- 500–6k mg (single dose)
- Suggested cadence
- once daily
Research behind this entry
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The Response of Alpha-Aminoadipic Acid to Short Term Lysine Ingestion in Healthy Individuals
Sixteen fasting healthy adults received 5 g of 13C-labelled lysine dihydrochloride. Labelled lysine and its 2-aminoadipic-acid metabolite appeared in plasma within 30 minutes and peaked on average at 2 hours, with…
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Comprehensive Safety Assessment of L-Lysine Supplementation from Clinical Studies
Systematic review identified 71 articles and 3,357 participants across doses from 16.8 mg to 17.5 g/day and durations up to 1,095 days. Reported adverse events were mainly gastrointestinal; the authors proposed a…
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Lysine Sources, Metabolism, Physiological Importance, and Use as a Supplement
Review maps intestinal transport, saccharopine and pipecolate catabolism, protein modifications, and proposed nutritional uses. It emphasizes unresolved questions and does not establish broad therapeutic efficacy from…
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Effect of lysine supplementation on health and morbidity in subjects belonging to poor peri-urban households in Accra, Ghana.
This citation reports a human clinical study involving L-Lysine. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
4 published studies referenced in the app, each with a plain-language summary.