Luteolin
Flavonoid
Luteolin is a plant flavone studied mostly in cell and animal models. Human clinical evidence is sparse and frequently confounded by combination products, so mechanistic findings should not be presented as proven disease treatment.
Pharmacokinetic model
A route-level PK model for luteolin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Flavonoid
- Suggested cadence
- once daily
Research behind this entry
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Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through a PPAR-gamma-dependent mechanism
Luteolin changed memory, amyloid, mitochondrial, and apoptosis measures in a transgenic Alzheimer mouse model and primary neurons. This is mechanistic preclinical evidence and does not demonstrate prevention or…
1 published study referenced in the app, each with a plain-language summary.