Lutein
Xanthophyll carotenoid concentrated in the macula and obtained from food or supplements. Evidence is formulation- and outcome-specific; cognitive trial meta-analysis has not shown a clear overall improvement.
Pharmacokinetic model
A route-level PK model for lutein is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Carotenoid
- Suggested cadence
- once daily
Research behind this entry
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Dietary Lutein and Cognitive Function in Adults: A Meta-Analysis of Randomized Controlled Trials
Meta-analysis of placebo-controlled trials found only small, statistically nonsignificant differences in attention, executive function, and memory. The authors considered maintenance signals hypothesis-generating and…
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Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.
This citation reports a human clinical study involving a formulation related to Lutein, not the isolated identity. The randomized trial used lutein with zeaxanthin and omega-3 fatty acids; isolated lutein effects cannot…
2 published studies referenced in the app, each with a plain-language summary.