Lipase (Digestive Enzyme)
Supplemental lipase may be porcine pancreatic lipase or one of several microbial enzymes with different activity, pH stability, coatings, and cofactors. Prescription pancreatic-enzyme replacement is not equivalent to an unspecified retail digestive-enzyme capsule.
Pharmacokinetic model
A route-level PK model for lipase (digestive enzyme) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Digestive Enzyme
- Suggested cadence
- once daily
Research behind this entry
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Lack of dose-response with Pancrease MT for the treatment of exocrine pancreatic insufficiency in adults
Adults with exocrine pancreatic insufficiency received enteric-coated pancreatic enzyme preparations containing 8,000 to 32,000 lipase units per dose. Higher strengths reduced fecal fat versus placebo without a clear…
1 published study referenced in the app, each with a plain-language summary.