Linalool
Monoterpene
Linalool is a chiral fragrance and plant monoterpene. Pure oral linalool, lavender oil, inhalation, and topical exposure require separate route and product models.
Pharmacokinetic model
A route-level PK model for linalool is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Monoterpene
- Suggested cadence
- once daily
Research behind this entry
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Development of a Liquid Chromatography-Tandem Mass Spectrometry Method for Characterizing Linalool Oral Pharmacokinetics in Humans
Ten adults received 100 mg oral linalool; mean Cmax was 85.5 ng/mL near 1.15 hours and mean apparent half-life was 3.9 hours with wide variability. This does not validate other routes or unspecified enantiomer mixtures.
1 published study referenced in the app, each with a plain-language summary.