Lemon Balm

Herb

Melissa officinalis herb used in teas and extracts for calming, sleep, and cognitive claims. Small acute studies report preparation- and dose-specific effects, including both favorable mood findings and slower performance on some timed tasks. Product chemistry and clinical evidence remain heterogeneous.

Pharmacokinetic model

A route-level PK model for lemon balm is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. Clinical Efficacy and Tolerability of Lemon Balm (Melissa officinalis L.) in Psychological Well-Being: A Review Mathews IM, Eastwood J, Lamport DJ, Cozannet RL, Fanca-Berthon P, Williams CM · Nutrients, 2024 DOI

    Review found preliminary signals for calming, mood, cognition, and sleep but emphasized heterogeneous preparations and the need for larger, rigorous randomized trials. Several authors reported industry affiliations,…

  2. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis Kennedy DO, Wake G, Savelev S, Tildesley NT, Perry EK, Wesnes KA, Scholey AB · Neuropsychopharmacology, 2003 DOI

    Double-blind crossover study gave 20 healthy young participants three single doses of one dried-leaf preparation or placebo. The highest dose increased calmness and selected memory scores, while lower doses were…

2 published studies referenced in the app, each with a plain-language summary.