Lactase
Lactase supplements hydrolyze dietary lactose in the gut. Effect depends on enzyme activity, timing relative to lactose, meal composition, product stability, and the cause of lactose malabsorption. It is not a systemic serum-tracked drug.
Pharmacokinetic model
A route-level PK model for lactase is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Digestive Enzyme
- Suggested cadence
- once daily
Research behind this entry
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Lactose intolerance: An update on its pathogenesis, diagnosis, and treatment
This review describes lactose malabsorption, diagnostic limitations, diet, and lactase replacement. It provides clinical context but is not primary evidence for a particular product or activity dose.
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Effect of lactase on symptoms and hydrogen breath levels in lactose intolerance: A crossover placebo-controlled study
In a randomized double-blind crossover study of 47 adults with breath-test-confirmed lactose intolerance, a lactase tablet reduced symptoms and cumulative breath hydrogen versus placebo. The result supports local…
2 published studies referenced in the app, each with a plain-language summary.