Kanna
Sceletium botanical preparations traditionally chewed or otherwise consumed and now sold as extracts for mood and stress claims. Reviews identify extensive phytochemical work but few clinical assessments, limited toxicology, and little bioavailability evidence.
Pharmacokinetic model
A route-level PK model for kanna is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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A Chewable Cure "Kanna": Biological and Pharmaceutical Properties of Sceletium tortuosum
Narrative review catalogued traditional use, plant chemistry, proposed pharmacology, and early commercial research. It emphasized the need to identify responsible bioactive compounds and critically confirm claimed…
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Skeletons in the closet? Using a bibliometric lens to visualise phytochemical and pharmacological activities linked to Sceletium, a mood enhancer
Bibliometric and literature analysis found diverse extraction and analytical methods but major gaps in toxicology, clinical assessment, bioavailability, and minor-alkaloid research. The authors concluded that little…
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Sceletium tortuosum (Zembrin® ) ameliorates experimentally induced anxiety in healthy volunteers.
This citation reports a human clinical study involving Kanna. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
3 published studies referenced in the app, each with a plain-language summary.