Jiaogulan
Gynostemma pentaphyllum is an herb marketed for metabolic and exercise support. Small randomized trials studied proprietary standardized extracts, so their results do not establish equivalence across products.
Pharmacokinetic model
A route-level PK model for jiaogulan is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial
Randomized placebo-controlled trial of the proprietary Actiponin extract. The result applies to that preparation and study population rather than every jiaogulan powder or extract.
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The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP) on body composition in overweight, adult men and women: A double-blind, randomised, placebo-controlled study
Randomized trial of the proprietary ActivAMP extract in overweight adults. Its formulation-specific findings do not validate other extracts or a generic concentration-time model.
2 published studies referenced in the app, each with a plain-language summary.