J147
Experimental Neuroprotective Compound
J147 is an experimental curcumin-derived phenotypic-screen compound studied in cell and animal neurodegeneration models. It is not an approved medicine or supplement and has no established human use.
Pharmacokinetic model
A route-level PK model for j147 is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Experimental Neuroprotective Compound
- Suggested cadence
- once daily
Research behind this entry
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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice
Aged transgenic Alzheimer-model mice received J147 in chow at an estimated 10 mg/kg/day for three months and underwent behavioral and tissue assays. The animal disease-model findings do not establish human efficacy,…
1 published study referenced in the app, each with a plain-language summary.