Hydroxytyrosol

Olive Polyphenol

Hydroxytyrosol is an olive-derived phenol whose absorption and metabolite profile vary substantially with the oil or food matrix.

Pharmacokinetic model

A route-level PK model for hydroxytyrosol is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Olive Polyphenol
Suggested cadence
once daily

Research behind this entry

  1. Pharmacokinetics and bioavailability of hydroxytyrosol are dependent on the food matrix in humans Alemán-Jiménez C, Domínguez-Perles R, Medina S, Prgomet I, López-González I, Simonelli-Muñoz A, Campillo-Cano M, Auñón D, Ferreres F, Gil-Izquierdo Á · European Journal of Nutrition, 2021 DOI

    Twenty volunteers ingested 5 mg hydroxytyrosol in different food matrices. Plasma and urinary exposure varied by matrix, with extra-virgin olive oil producing the highest early plasma concentration; one generic…

1 published study referenced in the app, each with a plain-language summary.