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High-fat meal

Foodoral · inferred

Meal with >30% kcal from fat (>15 g fat). Enhances absorption of lipophilic drugs (statins, certain azoles, isotretinoin, griseofulvin, cyclosporine) via bile-acid micellar solubilization and chylomicron transport.

Projected serum levels — 1 meal (≈ 1 mg), as needed (shown daily)

High-fat meal
High-fat meal modeled serum levels, 1 meal (≈ 1 mg) as needed (shown daily) over 15 days Population-based pharmacokinetic estimate. Steady state reached after approximately 7 days. 0 0.25 0.50 0.75 1 Day 0 Day 4 Day 8 Day 11 Day 15 Time on a regular schedule ≈ steady state · day 7

Maintenance schedule: 1 meal (≈ 1 mg) as needed (shown daily) (oral).

Modeled steady state after ~7 days: peak ≈ 0 mg, trough ≈ 0 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.

Key facts

Category
Food
Route modeled
Oral
Model confidence
inferred
Common dose
1 meal (≈ 1 mg)
Suggested maximum
3 meal/day
Reference dose range
1–3 meal (single dose)
Suggested cadence
as needed (shown daily)